First Short Notes of Clinical Parasitology (Amoebiasis Definition , Mode of Transmation, Life Cycle, Symptoms, Diagnosis and Treatment)

 

Amoebiasis is a disease caused by Entamoeba histolytica, leading to ulcers in the large intestine.

Mode of Transmission:

The disease spreads through the fecal-oral route, primarily via contaminated water, food, flies, or through contact with contaminated hands.

Life Cycle:

Entamoeba cysts are present in the environment and then enter the body through ingestion.

1. Cysts undergo nuclear duplication.

2. The nucleus quadruplicates.

3. Multiplication begins through division.

4. The fourth stage involves the transformation into trophozoites.

5. Trophozoites undergo binary division.

6. The pre-cyst stage precedes cyst formation.

Symptoms:

Symptoms typically manifest 1-4 weeks after infection, including:

·         Diarrhea

·         Presence of blood in stool

·         Abdominal cramps and pain

Diagnosis:

- Trophozoites observed in a Stool Examination.

- Cysts are identifiable in Sting Test of Stool.

Treatment:

Common treatments include Metronidazole and Tinidazole.